The Ribonuclease P database

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The Ribonuclease P Database

Ribonuclease P is the endoribonuclease responsible for the removal of leader sequences from tRNA precursors. Ribonuclease P is a ribonucleoprotein, and in bacteria the RNA alone is capable of pre-tRNA processing in vitro, i.e. it is a catalytic RNA. The Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary structures, three-dimensional models and a...

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Ribonuclease P.

The gene coding for the RNA subunit of ribonuclease P (RNase P) is essential in all free-living organisms. The RNA subunit, itself, is an enzyme and, from its evolutionary tree, we can infer that it is a very ancient molecule. The specificity of this enzyme is that it cleaves other RNA molecules at the junction of single-stranded and the 5' end of double-stranded regions of RNA. One can specula...

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Archaeal Ribonuclease P Has Multiple Protein Subunits Homologous to Eukaryotic Nuclear Ribonuclease P Subunits

HALL, THOMAS A. Archaeal Ribonuclease P has Multiple Protein Subunits Homologous to Eukaryotic Nuclear Ribonuclease P Subunits (Under the direction of James W. Brown.) RNase P removes the 5 ́ leader from all transfer RNA precursors, and is thus a required factor for protein synthesis. RNase P consists of a catalytic RNA molecule and associated protein, the amount of which varies among phylogenet...

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Ribonuclease P: the diversity of a ubiquitous RNA processing enzyme.

Ribonuclease P is the endonuclease required for generating the mature tRNA 5'-end. The ribonucleoprotein character of this enzyme has now been proven in most organisms and organelles. Exceptions, however, are still the chloroplasts, plant nuclei and animal mitochondria where no associated RNAs have been detected to date. In contrast to the known RNA subunits, which are fairly well-conserved in ...

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Comparative analysis of ribonuclease P RNA of the planctomycetes.

The planctomycetes, order Planctomycetales, are a distinct phylum of domain Bacteria. Genes encoding the RNA portion of ribonuclease P (RNase P) of some planctomycete members were sequenced and compared with existing database planctomycete sequences. rnpB gene sequences encoding RNase P RNA were generated by a conserved primer PCR strategy for Planctomyces brasiliensis, Planctomyces limnophilus...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1994

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/22.17.3660